Realism and fantasy collide in Jonathan Lethem’s genre-bending coming-of-age story, which follows two estranged brothers as they try to leave New York City for a new life in California only to find their plans–and lives–being forever changed by the appearance of a mysterious alien. We follow Paul (Paul Dano – Little Miss Sunshine, There Will Be Blood, Love And Mercy)–fresh from dropping out of college and living unhappily at home with his parents–as he arrives in New York City’s Washington Square Park in search of his younger brother Don, who was kicked out of their parents’ home a year earlier with neither Paul or their parents hearing from him since. Realizing their lives are at a dead end and looking to forge a new future together, Paul suggests that the two hop a plane for California and “leave all the bullshit behind.” After a robbery intended to raise money for their trip goes awry, the brothers find themselves being pursued not only by the drug dealers they ripped off, but by a sufferer: one of the sphinx-like creatures that roam the city, trailing after people in trouble. The brothers’ interaction with this fantastical creature turns the story on its head with both humorous and heart-wrenching results. What does the sufferer want and why is it following them? Has it come to help or hurt them? Is it a guardian angel or death angel? Like a walking enigma that eludes the explanations of all who encounter it, the brothers’ immutable new “friend” offers no easy answers.