Alumis Inc./$ALMS

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About Alumis Inc.

Alumis Inc is a clinical-stage biopharmaceutical company focused on identifying, acquiring, and accelerating the development and commercialization of transformative medicines for autoimmune disorders. The Company leverages its proprietary precision data analytics platform, biological insights, and a team of experts with deep experience in precision medicine drug discovery, development, and immunology, to create medicines that significantly improve the lives of patients by replacing broad immunosuppression with targeted therapies. Company pipeline includes: ESK-001, TYK2, A-OO5, IRF5.

Ticker

$ALMS

Sector

Health
Primary listing

Employees

183

Alumis Inc. Metrics

BasicAdvanced
$447M
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-$8.31
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Bulls say / Bears say

Alumis completed its merger with ACELYRIN in May 2025, creating a combined company with a pro forma cash position of approximately $737 million and extending its financial runway into 2027 (Nasdaq).
The company announced the completion of patient enrollment in its pivotal Phase 3 ONWARD program for ESK-001 with over 1,700 participants, positioning it to report topline data in early Q1 2026 (Nasdaq).
At ACTRIMS 2025, Alumis presented Phase 1 data demonstrating that A-005, its CNS-penetrant TYK2 inhibitor, successfully crosses the blood–brain barrier and is well tolerated, supporting a Phase 2 MS trial initiation in H2 2025 (BioSpace).
Alumis reported a net loss of $294.2 million for the year ended December 31, 2024, driven by R&D expenses of $265.6 million, highlighting a high cash burn and substantial operating losses (BioSpace).
Topline results from the pivotal Phase 3 ONWARD trial for ESK-001 are not expected until Q1 2026, leaving the stock exposed to prolonged clinical and regulatory risk without near-term catalysts (BioSpace).
A surprise cash bid by Concentra Biosciences for ACELYRIN introduces material risk to the completion of the Alumis–ACELYRIN merger, potentially undermining anticipated strategic and financial benefits (FierceBiotech).
Data summarised monthly by Lightyear AI. Last updated on 25 Jul 2025.
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
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