Candel Therapeutics/$CADL

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About Candel Therapeutics

Candel Therapeutics Inc is a clinical stage biopharmaceutical company focused on developing off-the-shelf viral immunotherapies that elicit an individualized, systemic anti-tumor immune response to help patients fight cancer. The immune cells induced by these viral immunotherapies are believed to target patients' specific tumor antigens, potentially improving responses in immunologically hot tumors while at the same time infiltrating the tumor microenvironment, transforming non-inflamed cold tumors with limited immune response into hot tumors. The company has established two clinical off-the-shelf viral immunotherapy platforms based on novel, genetically modified adenovirus and herpes simplex virus (HSV) constructs, respectively.
Ticker
$CADL
Sector
Health
Primary listing
NASDAQ
Employees
55

CADL Metrics

BasicAdvanced
$817M
-
-$1.44
-0.50
-

Bulls say / Bears say

The lead prostate-cancer program has meaningful late-stage validation: after a median 58-month follow-up in 745 patients, aglatimagene showed a 39% improvement in prostate-cancer-specific disease-free survival versus placebo, with no new safety signals reported. (Candel Therapeutics)
Candel initiated the global Phase 3 AURORA trial in NSCLC, supported by encouraging Phase 2a follow-up in which 50% of 46 per-protocol patients survived beyond 24 months and median overall survival was 25.4 months in evaluable patients. (Candel Therapeutics)
The balance sheet provides substantial near-term execution capacity: Candel reported $201.6 million of cash and equivalents at June 30, 2026, expects funding into Q1 2028, and has added EVERSANA plus an experienced chief commercial officer ahead of a potential 2027 launch. (Candel Therapeutics)
Candel remains dependent on regulatory execution: aglatimagene is not approved for any indication, while the prostate-cancer BLA is only planned for Q4 2026 and the NSCLC program is still in Phase 3. (Candel Therapeutics)
Cash consumption is accelerating as the company advances pivotal trials and manufacturing: Q2 2026 R&D expense rose to $19.8 million from $7.0 million, G&A increased to $6.9 million from $4.2 million, and net loss widened to $38.9 million from $4.8 million. (Candel Therapeutics)
Financing has increased potential shareholder and future-revenue dilution: Candel sold approximately $100 million of stock in February 2026 and entered a royalty deal that gives RTW a tiered single-digit percentage of U.S. aglatimagene sales, subject to a cap. (Candel Therapeutics)
Data summarised monthly by Lightyear AI. Last updated on 11 Sept 2026.

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