Enliven Therapeutics, Inc./$ELVN

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About Enliven Therapeutics, Inc.

Enliven Therapeutics Inc is a clinical-stage biopharmaceutical company focused on the discovery and development of small molecule therapeutics. The product candidates of the company include ELVN-001 is designed to specifically target the BCR-ABL fusion gene product, the oncogenic driver for patients with chronic myeloid leukemia (CML), ELVN-002 is designed to inhibit wild-type HER2 and key mutations of HER2.
Ticker
$ELVN
Sector
Health
Primary listing
NASDAQ
Employees
67

ELVN Metrics

BasicAdvanced
$4B
-
-$1.67
0.24
-

Bulls say / Bears say

ENABLE Phase 1b data show 61% overall major molecular response and 48% achieving MMR by 24 weeks at the 80 mg QD dose in refractory CML patients, demonstrating strong clinical activity for ELVN-001 (SEC)
Reached alignment with the FDA on key components of the ENABLE-2 Phase 3 2L+ trial design—confirming the 80 mg once-daily dose and second-line-and-beyond population—reducing regulatory risk for pivotal development (PRNewswire)
Closed an upsized public offering, raising approximately $460 million in gross proceeds, substantially strengthening the balance sheet to fund ELVN-001 pivotal trials into late-stage development (Investing.com)
Limited patient exposure and follow-up in the ENABLE Phase 1 trial—161 CML patients across dose levels as of March 10, 2026—may not adequately predict long-term safety and efficacy in broader populations (SEC)
Pipeline concentration risk persists as ELVN-002 remains in early Phase 1 monotherapy and combination cohorts while strategic alternatives are explored, limiting diversification beyond the CML program (Company Pipeline)
Enliven has never completed a clinical trial and has no approved products, heightening vulnerability to setbacks until ELVN-001’s Phase 3 readouts and regulatory approvals are achieved (SEC 10-Q)
Data summarised monthly by Lightyear AI. Last updated on 20 Aug 2026.
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