GH Research/$GHRS

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About GH Research

GH Research PLC is a clinical-stage biopharmaceutical company dedicated to transforming the lives of patients by developing a practice-changing treatment for depression. Its initial focus is on developing novel and proprietary mebufotenin therapies for the treatment of patients with Treatment-Resistant Depression, or TRD. Its portfolio currently includes GH001, a proprietary inhalable mebufotenin product candidate, and GH002, a proprietary intravenous mebufotenin product candidate. The group has only a single segment: Research and Development.

Ticker

$GHRS
Sector
Primary listing

Employees

50

Headquarters

Dublin, Ireland

GH Research Metrics

BasicAdvanced
$888M
-
-$0.73
0.97
-

What the Analysts think about GH Research

Analyst ratings (Buy, Hold, Sell) for GH Research stock.

Bulls say / Bears say

GH Research submitted its complete response to the FDA clinical hold for GH001 ahead of schedule in June 2025, reflecting strong regulatory engagement and possibly accelerating trial timelines (GlobeNewswire).
The Phase 2b GH001-TRD-201 trial achieved its primary endpoint with a highly significant 15.5-point placebo-adjusted reduction in MADRS score at Day 8 (p<0.0001), showing robust efficacy in treatment-resistant depression (Nasdaq).
Cash, cash equivalents, and marketable securities rose to $315.3 million as of March 31, 2025, providing considerable resources to support late-stage development and pivotal trials (GlobeNewswire).
The FDA’s clinical hold on the IND for GH001 remains unresolved, introducing regulatory uncertainty and potential delays for U.S. clinical development (GlobeNewswire).
Net loss increased to $10.8 million in Q1 2025 (from $7.7 million in Q1 2024), reflecting rising administrative expenses that may put future capital under pressure (GlobeNewswire).
GH002, the company’s intravenous mebufotenin candidate, is still in Phase 1 with an IND submission expected in Q4 2025, pushing out pipeline diversification and long-term value creation (GlobeNewswire).
Data summarised monthly by Lightyear AI. Last updated on 1 Nov 2025.

GH Research Financial Performance

Revenues and expenses
QuarterlyAnnual
Q3 24
QoQ growth
Revenue
$37B
-39.75%
Net income
$45B
107.52%
Profit margin
37.65%
6.78%

GH Research Earnings Performance

Company profitability
QuarterlyAnnual
Q4 23
Q1 24
Q2 24
Q3 24
Q4 24
Actual
$3.69
$2.85
$2.45
$2.42
-
Expected
$3.55
$2.61
$2.05
$2.31
$3.94
Surprise
3.94%
9.20%
19.51%
4.63%
-
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
Real-time US market data is sourced from the IEX order book provided by Polygon. After-hours US market data is 15 minutes delayed and may differ significantly from the actual tradable price at market open.

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