Ionis Pharmaceuticals/$IONS
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About Ionis Pharmaceuticals
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.
Ticker
$IONS
Sector
Primary listing
Industry
Biotechnology
Headquarters
Employees
1,069
ISIN
US4622221004
Website
IONS Metrics
BasicAdvanced
$6.3B
-
-$3.00
0.29
-
Price and volume
Market cap
$6.3B
Beta
0.29
52-week high
$52.34
52-week low
$23.95
Average daily volume
1.6M
Financial strength
Current ratio
9.664
Quick ratio
8.74
Long term debt to equity
409.112
Total debt to equity
408.824
Interest coverage (TTM)
-4.95%
Profitability
EBITDA (TTM)
-460.854
Gross margin (TTM)
-24.23%
Net profit margin (TTM)
-63.86%
Operating margin (TTM)
-65.75%
Effective tax rate (TTM)
1.31%
Revenue per employee (TTM)
$670,000
Management effectiveness
Return on assets (TTM)
-10.58%
Return on equity (TTM)
-118.62%
Valuation
Price to revenue (TTM)
8.406
Price to book
13.21
Price to tangible book (TTM)
13.2
Price to free cash flow (TTM)
-10.781
Free cash flow yield (TTM)
-9.28%
Free cash flow per share (TTM)
-366.49%
Growth
Revenue change (TTM)
-7.64%
Earnings per share change (TTM)
12.13%
3-year revenue growth (CAGR)
-5.14%
10-year revenue growth (CAGR)
11.18%
3-year earnings per share growth (CAGR)
377.35%
10-year earnings per share growth (CAGR)
30.66%
What the Analysts think about IONS
Analyst ratings (Buy, Hold, Sell) for Ionis Pharmaceuticals stock.
Bulls say / Bears say
Ionis Pharmaceuticals received FDA approval for Tryngolza (olezarsen) in December 2024, marking its first independent drug launch and potentially boosting revenue streams. (Wikipedia)
Jefferies raised its price target for Ionis to $77, citing positive early data for its Angelman syndrome treatment, IONS582, and increased sales forecasts. (Investing.com)
Ionis reported a 10.9% year-over-year revenue increase in Q1 2025, surpassing analyst expectations and indicating strong financial performance. (TradingView News)
Ionis announced a $500 million stock offering in September 2024, which could dilute existing shareholders' value. (Investing.com)
BMO Capital Markets reduced its price target for Ionis to $45 in February 2025, reflecting concerns over the company's valuation. (Defense World)
Ionis reported a quarterly loss of $147 million in Q1 2025, indicating ongoing profitability challenges. (TradingView News)
Data summarised monthly by Lightyear AI. Last updated on 7 Jun 2025.
IONS Financial Performance
Revenues and expenses
IONS Earnings Performance
Company profitability
IONS News
AllArticlesVideos
Ionis announces Biogen to advance salanersen into SMA registrational studies based on positive interim Phase 1 results
Business Wire·6 days ago
Ionis to host 2025 virtual Annual Meeting of Stockholders
Business Wire·2 months ago
Ionis Pharmaceuticals Narrows Q1 Loss, Lifts Revenue Forecast While Drug Sales Surge
Benzinga·2 months ago
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
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Capital at risk
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FAQs
What’s the current market cap for Ionis Pharmaceuticals stock?
Ionis Pharmaceuticals (IONS) has a market cap of $6.3B as of July 01, 2025.
What is the P/E ratio for Ionis Pharmaceuticals stock?
The price to earnings (P/E) ratio for Ionis Pharmaceuticals (IONS) stock is 0 as of July 01, 2025.
Does Ionis Pharmaceuticals stock pay dividends?
No, Ionis Pharmaceuticals (IONS) stock does not pay dividends to its shareholders as of July 01, 2025.
When is the next Ionis Pharmaceuticals dividend payment date?
Ionis Pharmaceuticals (IONS) stock does not pay dividends to its shareholders.
What is the beta indicator for Ionis Pharmaceuticals?
Ionis Pharmaceuticals (IONS) has a beta rating of 0.29. This means that it is less volatile than the market, on average. A beta of 1 would indicate the stock moves in-line with the market, while a beta of 0.5 would mean it moves half as much as the market.