Ionis Pharmaceuticals/$IONS
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About Ionis Pharmaceuticals
Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.
Ticker
$IONS
Sector
Health
Primary listing
Employees
1,069
Headquarters
Website
IONS Metrics
BasicAdvanced
$6.5B
-
-$1.72
0.25
-
Price and volume
Market cap
$6.5B
Beta
0.25
52-week high
$50.43
52-week low
$23.95
Average daily volume
2.1M
Financial strength
Current ratio
2.872
Quick ratio
2.614
Long term debt to equity
210.601
Total debt to equity
310.285
Interest coverage (TTM)
-2.92%
Profitability
EBITDA (TTM)
-255.171
Gross margin (TTM)
5.22%
Net profit margin (TTM)
-28.43%
Operating margin (TTM)
-28.23%
Effective tax rate (TTM)
2.21%
Revenue per employee (TTM)
$880,000
Management effectiveness
Return on assets (TTM)
-5.87%
Return on equity (TTM)
-59.91%
Valuation
Price to revenue (TTM)
6.75
Price to book
10.29
Price to tangible book (TTM)
10.29
Price to free cash flow (TTM)
-22.557
Free cash flow yield (TTM)
-4.43%
Free cash flow per share (TTM)
-1.811
Growth
Revenue change (TTM)
16.05%
Earnings per share change (TTM)
-31.79%
3-year revenue growth (CAGR)
3.61%
10-year revenue growth (CAGR)
11.71%
3-year earnings per share growth (CAGR)
105.41%
10-year earnings per share growth (CAGR)
24.66%
What the Analysts think about IONS
Analyst ratings (Buy, Hold, Sell) for Ionis Pharmaceuticals stock.
IONS Financial Performance
Revenues and expenses
IONS Earnings Performance
Company profitability
IONS News
AllArticlesVideos
Ionis Posts Surprise Q2 Profit, Double Revenues On Stronger Sales From Newly Approved Genetic Disease Drug
Benzinga·2 weeks ago
TRYNGOLZA® (olezarsen) recommended for approval in the EU by CHMP for familial chylomicronemia syndrome (FCS)
Business Wire·3 weeks ago
Ionis Pharmaceuticals founder Stanley Crooke on the fight against rare diseases
CNBC Television·3 weeks ago
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Upcoming events
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FAQs
What’s the current market cap for Ionis Pharmaceuticals stock?
Ionis Pharmaceuticals (IONS) has a market cap of $6.5B as of August 12, 2025.
What is the P/E ratio for Ionis Pharmaceuticals stock?
The price to earnings (P/E) ratio for Ionis Pharmaceuticals (IONS) stock is 0 as of August 12, 2025.
Does Ionis Pharmaceuticals stock pay dividends?
No, Ionis Pharmaceuticals (IONS) stock does not pay dividends to its shareholders as of August 12, 2025.
When is the next Ionis Pharmaceuticals dividend payment date?
Ionis Pharmaceuticals (IONS) stock does not pay dividends to its shareholders.
What is the beta indicator for Ionis Pharmaceuticals?
Ionis Pharmaceuticals (IONS) has a beta rating of 0.25. This means that it is less volatile than the market, on average. A beta of 1 would indicate the stock moves in-line with the market, while a beta of 0.5 would mean it moves half as much as the market.