MBX Biosciences, Inc./$MBX

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About MBX Biosciences, Inc.

MBX Biosciences Inc is a clinical stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders. The company designed its proprietary Precision Endocrine Peptide, or PEP, platform to overcome the key limitations of unmodified and modified peptide therapies to improve clinical outcomes and simplify disease management for patients. Its PEPs are selectively engineered to have optimized pharmaceutical properties, including extended time-action profiles and consistent drug concentrations with low peak-to-trough concentration ratios, consistent exposure to target tissues, and less frequent dosing. Its product candidates include MBX 2109, MBX 1416, and MBX 4291.

Ticker

$MBX
Sector
Primary listing

Employees

43

MBX Metrics

BasicAdvanced
$727M
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-$2.88
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Bulls say / Bears say

MBX ended Q2 2025 with $224.9 million in cash, cash equivalents and marketable securities, providing a runway into mid-2027 and reducing near-term financing risk. (GLOBE NEWSWIRE)
Once-weekly canvuparatide met its primary composite endpoint in the Phase 2 Avail trial, achieving a 63% responder rate at 12 weeks and 79% at 6 months with a favorable safety profile, de-risking its Phase 3 initiation. (MBX Biosciences)
MBX submitted an IND for MBX 4291 on June 16, 2025 and remains on track to initiate its Phase 1 trial in Q3 2025, broadening its pipeline into the high-potential obesity market. (GLOBE NEWSWIRE)
With no approved products, MBX’s valuation hinges on upcoming binary clinical readouts for canvuparatide topline data in Q3 2025 and first-in-human results for MBX 4291 in 2027. (GLOBE NEWSWIRE)
MBX’s cash position declined by ~$37.2 million from $262.1 million at year-end 2024 to $224.9 million at June 30, 2025, indicating a high burn rate that could pressure financing if milestones slip. (GLOBE NEWSWIRE)(GLOBE NEWSWIRE)
MBX 4291 faces an obesity market dominated by Novo Nordisk’s Wegovy and Eli Lilly’s Mounjaro/Zepbound, which hold the majority GLP-1 share and leverage extensive R&D and commercial infrastructure. (Reuters)
Data summarised monthly by Lightyear AI. Last updated on 2 Oct 2025.
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