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Vaxcyte/$PCVX

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About Vaxcyte

Vaxcyte Inc is a clinical-stage vaccine company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. It uses the XpressCF cell-free protein synthesis platform to develop potentially superior and novel conjugate and protein vaccine candidates for adult and pediatric indications. The company's product pipeline includes: VAX-31, VAX-24, and VAX-XL PCV vaccine candidates; VAX-A1, a Novel Group A Strep Vaccine; and VAX-GI, a Novel Shigella Vaccine, among others, in their different stages of development.
Ticker
$PCVX
Sector
Health
Primary listing
NASDAQ
Employees
507

Vaxcyte Metrics

BasicAdvanced
$9.8B
-
-$7.65
1.21
-

What the Analysts think about Vaxcyte

Analyst ratings (Buy, Hold, Sell) for Vaxcyte stock.
Analyst projections of the future price of Vaxcyte stock.

Bulls say / Bears say

VAX-31 cleared OPUS-1’s prespecified primary immunogenicity endpoints, matching licensed vaccines on shared serotypes and showing a similar safety profile. This is a strong first pivotal result for the adult programme. (Vaxcyte)
Its 31-serotype design could offer broader coverage than the current 20- and 21-valent adult vaccines. In OPUS-1, VAX-31 also showed superiority for three serotypes unique to the candidate, which may help it stand out if approved. (BioPharma Dive, Vaxcyte)
Vaxcyte has completed enrolment in all three adult Phase 3 trials, with results from OPUS-2 and OPUS-3 expected in the first half of 2027. Those readouts, alongside infant-study results, provide a series of near-term catalysts for the programme. (Vaxcyte)
In the individual comparison with Merck’s Capvaxive, VAX-31 missed the more stringent non-inferiority threshold for two of 19 shared serotypes, although both met the historical threshold. This leaves a potential point of concern in direct comparisons with a marketed rival. (Vaxcyte, BioPharma Dive)
OPUS-1 is only part of the evidence package: the company still needs OPUS-2 and OPUS-3 results and a manufacturing consistency study before its planned BLA filing in the first half of 2028. Delays or weaker findings could push back the regulatory and launch timetable. (Vaxcyte)
The programme is expensive: Vaxcyte reported a $284.3 million net loss in the second quarter of 2026. Its subsequent $1.15 billion financing included common shares, pre-funded warrants and convertible notes, creating dilution and debt risks for shareholders. (Vaxcyte, Vaxcyte)
Data summarised monthly by Lightyear AI. Last updated on 1 Nov 2026.

Vaxcyte Financial Performance

Revenues and expenses
Income statement
QuarterlyAnnual
Q3 24
QoQ growth
Revenue
Net income
Profit margin

Vaxcyte Earnings Performance

Company profitability
Earnings per share
QuarterlyAnnual
Q4 23
Q1 24
Q2 24
Q3 24
Q4 24
Actual
Expected
Surprise
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