Rhythm Pharmaceuticals/$RYTM
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About Rhythm Pharmaceuticals
Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company. It is engaged in the development and commercialization of therapies for patients with rare diseases. The company is focused on its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. Geographically the company generates its revenue from the United States and internationally with the majority being generated from the United States.
Ticker
$RYTM
Sector
Primary listing
Employees
283
Headquarters
Website
RYTM Metrics
BasicAdvanced
$6.4B
-
-$3.02
2.39
-
Price and volume
Market cap
$6.4B
Beta
2.39
52-week high
$106.52
52-week low
$45.91
Average daily volume
595K
Financial strength
Current ratio
2.786
Quick ratio
2.45
Long term debt to equity
82.117
Total debt to equity
85.327
Interest coverage (TTM)
-7.90%
Profitability
EBITDA (TTM)
-175.91
Gross margin (TTM)
89.25%
Net profit margin (TTM)
-117.16%
Operating margin (TTM)
-113.53%
Effective tax rate (TTM)
0.01%
Revenue per employee (TTM)
$550,000
Management effectiveness
Return on assets (TTM)
-44.70%
Return on equity (TTM)
-116.97%
Valuation
Price to revenue (TTM)
38.413
Price to book
-516.44
Price to tangible book (TTM)
-348.33
Price to free cash flow (TTM)
-55.473
Free cash flow yield (TTM)
-1.80%
Free cash flow per share (TTM)
-1.735
Growth
Revenue change (TTM)
53.55%
Earnings per share change (TTM)
-31.00%
3-year revenue growth (CAGR)
126.73%
3-year earnings per share growth (CAGR)
-4.73%
10-year earnings per share growth (CAGR)
27.01%
What the Analysts think about RYTM
Analyst ratings (Buy, Hold, Sell) for Rhythm Pharmaceuticals stock.
Bulls say / Bears say
Global sales of IMCIVREE (setmelanotide) grew 29% sequentially to $48.5 million in Q2 2025, driven by strong uptake in Bardet-Biedl syndrome, with U.S. revenue up 31% quarter-on-quarter to $32.0 million (GlobeNewswire).
Rhythm is on track to submit U.S. and EU filings for setmelanotide in acquired hypothalamic obesity in Q3 2025, positioning the company for a potential label expansion into a new rare disease indication (GlobeNewswire).
The Phase 2 trial of oral MC4R agonist bivamelagon met its primary endpoint with BMI reductions of 9.3% at the 600 mg dose (p=0.0004) and 7.7% at 400 mg (p=0.0002), and Phase 3 TRANSCEND data showed a –19.8% placebo-adjusted BMI reduction in acquired hypothalamic obesity, underscoring strong clinical differentiation (GlobeNewswire).
Rhythm’s net loss widened to $48.0 million in Q2 2025, or $0.75 per share, compared with a $33.6 million loss ($0.55 per share) a year earlier, reflecting increased expense pressure (GlobeNewswire).
Cash, cash equivalents and short-term investments fell to $291.0 million as of June 30, 2025, down from $320.6 million at year-end 2024, excluding the $189.2 million raised in July, underscoring ongoing cash burn from R&D and SG&A (GlobeNewswire).
R&D expenses rose to $42.3 million and SG&A to $45.9 million in Q2 2025, increases that outpaced revenue growth and may pressure margins until new indications broaden the commercial base (GlobeNewswire).
Data summarised monthly by Lightyear AI. Last updated on 2 Sept 2025.
RYTM Financial Performance
Revenues and expenses
RYTM Earnings Performance
Company profitability
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Capital at risk
Upcoming events
No upcoming events
FAQs
What’s the current market cap for Rhythm Pharmaceuticals stock?
Rhythm Pharmaceuticals (RYTM) has a market cap of $6.4B as of September 15, 2025.
What is the P/E ratio for Rhythm Pharmaceuticals stock?
The price to earnings (P/E) ratio for Rhythm Pharmaceuticals (RYTM) stock is 0 as of September 15, 2025.
Does Rhythm Pharmaceuticals stock pay dividends?
No, Rhythm Pharmaceuticals (RYTM) stock does not pay dividends to its shareholders as of September 15, 2025.
When is the next Rhythm Pharmaceuticals dividend payment date?
Rhythm Pharmaceuticals (RYTM) stock does not pay dividends to its shareholders.
What is the beta indicator for Rhythm Pharmaceuticals?
Rhythm Pharmaceuticals (RYTM) has a beta rating of 2.39. This means that it is more volatile than the market, on average. A beta of 1 would indicate the stock moves in-line with the market, while a beta of 2 would indicate the stock moves twice as much as the market.