Trevi Therapeutics/$TRVI

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About Trevi Therapeutics

Trevi Therapeutics Inc is a clinical-stage biopharmaceutical company focused on the development and commercialization of the investigational therapy Haduvio (oral nalbuphine ER) for the treatment of chronic cough in adults with idiopathic pulmonary fibrosis, or IPF, and other chronic cough indications, and for the treatment of prurigo nodularis. Haduvio is an oral extended-release formulation of nalbuphine.

Ticker

$TRVI
Sector
Primary listing

Employees

33

TRVI Metrics

BasicAdvanced
$1.2B
-
-$0.42
0.59
-

What the Analysts think about TRVI

Analyst ratings (Buy, Hold, Sell) for Trevi Therapeutics stock.

Bulls say / Bears say

Topline data from the Phase 2b CORAL trial showed Haduvio achieved up to a 60.2% reduction in 24-hour cough frequency at the 108 mg BID dose (p<0.0001), meeting the primary endpoint across all dose groups (Trevi Therapeutics IR)
Additional analyses from the Phase 2a RIVER trial demonstrated statistically significant responder rates at 30%, 50%, and 75% thresholds and improvements in the Leicester Cough Questionnaire, reinforcing Haduvio’s consistent efficacy across multiple endpoints (p<0.0001) (Trevi Therapeutics IR)
In Q2 2025, Trevi closed a $115.1 million underwritten offering, bolstering its balance sheet and providing an expected cash runway into 2029 to fund ongoing development of Haduvio (PR Newswire)
Phase 3 pivotal trials are not expected to begin until the first half of 2026, delaying potential regulatory approval and commercial launch by at least 18 months (Trevi Therapeutics IR)
As of Q1 2025, Trevi held $103.3 million in cash with a runway only through Q4 2026, raising the risk of further dilutive financing before Haduvio could reach commercialization (Trevi Therapeutics IR)
In the Phase 2b CORAL trial, common adverse events—including nausea, vomiting, constipation, dizziness, headache, and fatigue—were reported, which could limit patient tolerability and adherence (Trevi Therapeutics IR)
Data summarised monthly by Lightyear AI. Last updated on 5 Oct 2025.

TRVI Financial Performance

Revenues and expenses
QuarterlyAnnual
Q3 24
QoQ growth
Revenue
$37B
-39.75%
Net income
$45B
107.52%
Profit margin
37.65%
6.78%

TRVI Earnings Performance

Company profitability
QuarterlyAnnual
Q4 23
Q1 24
Q2 24
Q3 24
Q4 24
Actual
$3.69
$2.85
$2.45
$2.42
-
Expected
$3.55
$2.61
$2.05
$2.31
$3.94
Surprise
3.94%
9.20%
19.51%
4.63%
-
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
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