Upstream Bio, Inc./$UPB
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About Upstream Bio, Inc.
Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.
Ticker
$UPB
Sector
Primary listing
Employees
52
Headquarters
Website
UPB Metrics
BasicAdvanced
$1.5B
-
-$2.62
-
-
Price and volume
Market cap
$1.5B
52-week high
$33.00
52-week low
$5.14
Average daily volume
461K
Financial strength
Current ratio
32.669
Quick ratio
31.469
Long term debt to equity
0.186
Total debt to equity
0.375
Profitability
EBITDA (TTM)
-140.332
Gross margin (TTM)
100.00%
Net profit margin (TTM)
-4,366.77%
Operating margin (TTM)
-5,020.08%
Revenue per employee (TTM)
$50,000
Management effectiveness
Return on assets (TTM)
-28.15%
Return on equity (TTM)
-40.80%
Valuation
Price to revenue (TTM)
501.849
Price to book
3.87
Price to tangible book (TTM)
3.87
Price to free cash flow (TTM)
-11.462
Free cash flow yield (TTM)
-8.72%
Free cash flow per share (TTM)
-2.368
Growth
Revenue change (TTM)
26.82%
Earnings per share change (TTM)
-86.07%
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Capital at risk
Upcoming events
No upcoming events
FAQs
What’s the current market cap for Upstream Bio, Inc. stock?
Upstream Bio, Inc. (UPB) has a market cap of $1.5B as of December 13, 2025.
What is the P/E ratio for Upstream Bio, Inc. stock?
The price to earnings (P/E) ratio for Upstream Bio, Inc. (UPB) stock is 0 as of December 13, 2025.
Does Upstream Bio, Inc. stock pay dividends?
No, Upstream Bio, Inc. (UPB) stock does not pay dividends to its shareholders as of December 13, 2025.
When is the next Upstream Bio, Inc. dividend payment date?
Upstream Bio, Inc. (UPB) stock does not pay dividends to its shareholders.
What is the beta indicator for Upstream Bio, Inc.?
Upstream Bio, Inc. (UPB) does not currently have a Beta indicator.