Vertex Pharmaceuticals/$VRTX

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About Vertex Pharmaceuticals

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Ticker

$VRTX
Sector
Primary listing

Employees

6,100

VRTX Metrics

BasicAdvanced
$100B
27.62
$14.07
0.44
-

What the Analysts think about VRTX

Analyst ratings (Buy, Hold, Sell) for Vertex Pharmaceuticals stock.

Bulls say / Bears say

Vertex reported Q2 2025 revenue of $2.96 billion, up 12% year-on-year, and adjusted EPS of $4.52, both beating Wall Street estimates on sustained demand for its cystic fibrosis therapies (Reuters)
The European Union’s approval of Alyftrek, a once-daily cystic fibrosis treatment, strengthens Vertex’s global CF franchise and extends its standard-of-care leadership (Reuters)
Management maintained full-year 2025 revenue guidance of $11.85–12.00 billion despite a late-stage trial setback, reflecting confidence in its core CF business and minimal impact from external headwinds (Reuters)
Vertex discontinued development of its experimental non-opioid painkiller VX-993 after a mid-stage trial failed to show statistical efficacy, sending shares down about 12% and raising questions on its pain portfolio diversification (Reuters)
The company halted plans to study Journavx for nerve pain in the lower back and legs after FDA discussions, undermining expectations for non-CF revenue growth and dampening investor sentiment (Reuters)
Journavx has accrued only 79,763 prescriptions since launch, a slower uptake than analysts anticipated, putting pressure on its contribution to offset reliance on cystic fibrosis revenues (Reuters)
Data summarised monthly by Lightyear AI. Last updated on 4 Sept 2025.

VRTX Financial Performance

Revenues and expenses
QuarterlyAnnual
Q3 24
QoQ growth
Revenue
$37B
-39.75%
Net income
$45B
107.52%
Profit margin
37.65%
6.78%

VRTX Earnings Performance

Company profitability
QuarterlyAnnual
Q4 23
Q1 24
Q2 24
Q3 24
Q4 24
Actual
$3.69
$2.85
$2.45
$2.42
-
Expected
$3.55
$2.61
$2.05
$2.31
$3.94
Surprise
3.94%
9.20%
19.51%
4.63%
-
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
Real-time US market data is sourced from the IEX order book provided by Polygon. After-hours US market data is 15 minutes delayed and may differ significantly from the actual tradable price at market open.

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