Lexicon Pharmaceuticals/$LXRX

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About Lexicon Pharmaceuticals

Lexicon Pharmaceuticals Inc is a biopharmaceutical company. It is engaged in the discovery, development, and commercialization of pharmaceutical products for the treatment of human diseases. Some of its drug candidates are LX9211, an orally-delivered small molecule drug candidate, also developing LX9851, an orally-delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic.

Ticker

$LXRX
Sector
Primary listing

Employees

103

LXRX Metrics

BasicAdvanced
$501M
-
-$0.33
1.24
-

What the Analysts think about LXRX

Analyst ratings (Buy, Hold, Sell) for Lexicon Pharmaceuticals stock.

Bulls say / Bears say

Novo Nordisk has signed a licensing deal for Lexicon’s obesity drug candidate LX9851 worth up to $1 billion, including $75 million in upfront and near-term payments, affirming Lexicon’s obesity pipeline value and strengthening its financial footing.
Topline Phase 2b PROGRESS results show that pilavapadin (LX9211) at a 10 mg dose delivered meaningful pain relief compared to placebo with good tolerability, supporting its progress to Phase 3 trials.
Lexicon shares nearly doubled in premarket trading following the Novo Nordisk deal, reflecting strong market confidence in its pipeline.
FDA has postponed its review of additional data for Zynquista until Q4 2025, delaying any approval decision and associated revenue opportunities.
A complete response letter from the FDA in December 2024 flagged concerns about a higher risk of diabetic ketoacidosis with Zynquista, weakening confidence in its safety profile.
Lexicon plans to cut approximately 60% of its workforce after FDA shortcomings in its diabetes drug application, which could restrict its commercial and operational capabilities.
Data summarised monthly by Lightyear AI. Last updated on 2 Nov 2025.

LXRX Financial Performance

Revenues and expenses
QuarterlyAnnual
Q3 24
QoQ growth
Revenue
$37B
-39.75%
Net income
$45B
107.52%
Profit margin
37.65%
6.78%

LXRX Earnings Performance

Company profitability
QuarterlyAnnual
Q4 23
Q1 24
Q2 24
Q3 24
Q4 24
Actual
$3.69
$2.85
$2.45
$2.42
-
Expected
$3.55
$2.61
$2.05
$2.31
$3.94
Surprise
3.94%
9.20%
19.51%
4.63%
-
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
Real-time US market data is sourced from the IEX order book provided by Polygon. After-hours US market data is 15 minutes delayed and may differ significantly from the actual tradable price at market open.

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