Pacific Biosciences/$PACB

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About Pacific Biosciences

Pacific Biosciences of California Inc is a biotechnology company focused on designing, developing, and manufacturing sequencing solutions that enable scientists and clinical researchers to improve their understanding of the genome and ultimately, resolve genetically complex problems. It operates in, one reportable segment: the development, manufacturing, and marketing of an integrated platform for genetic analysis. The majority of the company's revenue is derived from Americas, followed by Asia-Pacific and Europe Middle East, and Africa.

Ticker

$PACB
Sector
Primary listing

Employees

575

PACB Metrics

BasicAdvanced
$529M
-
-$1.71
2.32
-

What the Analysts think about PACB

Analyst ratings (Buy, Hold, Sell) for Pacific Biosciences stock.

Bulls say / Bears say

PacBio is growing its share of the long-read sequencing market in China by strengthening and expanding its distribution agreement with Haorui Gene amid an import ban on Illumina sequencers, positioning itself as a key supplier to clinical and research labs throughout the region. (FierceBiotech)
PacBio signed a partnership with Roche Diagnostics to co-develop clinical in-vitro diagnostic products, receiving $35 million upfront and up to $40 million in milestone payments, which bolsters its clinical commercial strategy and diversifies its revenue base. (DrugDiscoveryNews)
A study covered by RTTNews in the American Journal of Human Genetics reported PacBio’s HiFi sequencing achieved a 93% diagnostic rate in 100 challenging rare disease cases, demonstrating its technical edge and potential to streamline and consolidate multiple diagnostic workflows. (Nasdaq)
PacBio is set to cut around 120 jobs and reduce annual adjusted operating expenses by $45–$50 million due to NIH funding reductions and new tariffs, highlighting significant short-term cost challenges even though revenue guidance remains unchanged. (Reuters)
Uncertainty surrounding funding in U.S. academia and changes in NIH policies have eroded investor confidence and led to a steep drop in sales of high-priced instruments, forcing PacBio to make layoffs and implement widespread cost cuts. (Barron's)
First quarter 2025 revenue from the Americas declined by 8% compared to the prior year, underscoring how instrument placements are highly sensitive to changes in academic and government research funding. (Barron's)
Data summarised monthly by Lightyear AI. Last updated on 3 Nov 2025.

PACB Financial Performance

Revenues and expenses
QuarterlyAnnual
Q3 24
QoQ growth
Revenue
$37B
-39.75%
Net income
$45B
107.52%
Profit margin
37.65%
6.78%

PACB Earnings Performance

Company profitability
QuarterlyAnnual
Q4 23
Q1 24
Q2 24
Q3 24
Q4 24
Actual
$3.69
$2.85
$2.45
$2.42
-
Expected
$3.55
$2.61
$2.05
$2.31
$3.94
Surprise
3.94%
9.20%
19.51%
4.63%
-
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
Real-time US market data is sourced from the IEX order book provided by Polygon. After-hours US market data is 15 minutes delayed and may differ significantly from the actual tradable price at market open.

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