Opus Genetics/$IRD
1D1W1MYTD1Y5YMAX
Capital at risk
About Opus Genetics
Opus Genetics Inc is a clinical-stage ophthalmic biopharmaceutical company developing therapies to treat patients with inherited retinal diseases (IRDs) and therapies to treat patients with other retinal and refractive disorders. The pipeline includes seven adeno-associated virus (AAV)-based programs, led by OPGx-LCA5 for LCA5-related mutations and OPGx-BEST1 for BEST1-related retinal degeneration, with additional candidates targeting RHO, CNGB1, RDH12, NMNAT1, and MERTK. The company operates in one operating segment, which is the business of developing products related to vision performance and health.
- Ticker
- $IRD
- Sector
- Health
- Primary listing
- NASDAQ
- Employees
- 28
- Headquarters
- Durham, United States
- Website
- opusgtx.com
Opus Genetics Metrics
BasicAdvanced
$431M
-
-$1.29
0.58
-
Price and volume
Market cap
$431M
Beta
0.58
52-week high
$7.07
52-week low
$1.42
Average daily volume
3.6M
Financial strength
Current ratio
12.189
Quick ratio
11.87
Long term debt to equity
-2.788
Total debt to equity
-2.788
Interest coverage (TTM)
-221.00%
Profitability
EBITDA (TTM)
-50.555
Gross margin (TTM)
-291.85%
Net profit margin (TTM)
-1,091.82%
Operating margin (TTM)
-513.47%
Revenue per employee (TTM)
$350,000
Management effectiveness
Return on assets (TTM)
-48.06%
Return on equity (TTM)
-4,796.52%
Valuation
Price to revenue (TTM)
43.87
Price to book
-32.97
Price to tangible book (TTM)
-32.97
Price to free cash flow (TTM)
-10.632
Free cash flow yield (TTM)
-9.41%
Free cash flow per share (TTM)
-0.487
Growth
Revenue change (TTM)
-36.09%
Earnings per share change (TTM)
-14.65%
3-year revenue growth (CAGR)
-39.84%
3-year earnings per share growth (CAGR)
14.09%
What the Analysts think about Opus Genetics
Analyst ratings (Buy, Hold, Sell) for Opus Genetics stock.
Analyst projections of the future price of Opus Genetics stock.
Bulls say / Bears say
OPGx-BEST1 produced positive early proof-of-concept data: all five Cohort 1 participants showed clinically meaningful visual-function improvement, four showed structural improvement, and no serious adverse events or dose-limiting toxicities were observed. (Opus Genetics)
Opus completed enrollment in the registrational OPGx-LCA5 Phase 3 trial after FDA alignment on the design, with dosing expected to begin in Q4 2026. The program could support a relatively near-term regulatory catalyst in an ultra-rare disease with no established genetic treatment. (Opus Genetics)
The company reported cash and cash equivalents of $88.8 million at June 30, 2026 and expects available resources to fund operations into 2029, supporting multiple clinical programs and upcoming inflection points across LCA5, BEST1, RDH12, MERTK and RHO. (Opus Genetics)
OPGx-BEST1’s encouraging results are based on only five participants in an open-label Phase 1/2 cohort, with interim data that the company says may change materially as follow-up continues; efficacy therefore remains unproven in a controlled pivotal setting. (Opus Genetics)
Opus remains loss-making and noncommercial: Q2 2026 revenue was only $0.8 million, while R&D expense rose to $11.2 million and the quarterly net loss was $8.1 million. Continued clinical expansion will require substantial spending before any product revenue is generated. (Opus Genetics)
The financing plan reduces near-term liquidity risk but adds execution and capital-structure risk: the Oberland facility is secured, bears interest, and much of the potential $155 million is conditional on future funding conditions or milestones; the company also issued $5 million of equity. (SEC)
Data summarised monthly by Lightyear AI. Last updated on 9 Sept 2026.
Opus Genetics Financial Performance
Revenues and expenses
Opus Genetics Earnings Performance
Company profitability
Upcoming events
No upcoming events
Funds containing Opus Genetics
Fund name | Fund size | $IRD weighting |
|---|---|---|
SPDR Russell 2000 US Small Cap€R2US | €4.8B | 0.00% |
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