Vaxcyte/$PCVX

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About Vaxcyte

Vaxcyte Inc is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. It is developing broad-spectrum conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Its product comprises of Pneumococcal conjugate vaccine. The firm's product candidate consists of VAX-31, VAX-24, VAX-A1, VAX-PG, VAX-GI, and Others.

Ticker

$PCVX
Sector
Primary listing

Employees

414

Vaxcyte Metrics

BasicAdvanced
$4B
-
-$4.13
1.21
-

What the Analysts think about Vaxcyte

Analyst ratings (Buy, Hold, Sell) for Vaxcyte stock.

Bulls say / Bears say

Vaxcyte’s balance sheet remains robust, with cash, cash equivalents and investments of $2.83 billion as of June 30, 2025, underpinning the current operating plan through mid-2028 and funding late-stage PCV development without near-term financing needs (Nasdaq via turn6search3).
The VAX-24 infant Phase 2 dose-finding study delivered positive topline results in March 2025, demonstrating safety and tolerability comparable to Prevnar 20 and robust immunogenicity across all doses, leading to selection of a mid-dose formulation for advancement to a potential Phase 3 program (GlobeNewswire via turn1search0).
Constructive FDA engagement—including input during an End-of-Phase 2 meeting and ongoing Breakthrough Therapy discussions—has streamlined VAX-31’s adult Phase 3 program design, with guidance on CMC and non-inferiority endpoints paving the way for a fourth-quarter 2025 trial initiation and supporting a potential BLA submission upon study completion (GlobeNewswire via turn5search1).
Pipeline narrowing reduces Vaxcyte’s long-term diversification, as the company paused advancement of early-stage candidates VAX-A1 (Group A Strep) and VAX-GI (Shigella) and discontinued VAX-PG (periodontal disease), concentrating resources on PCV programs at the expense of potential revenue streams beyond pneumococcal vaccines (Nasdaq via turn8search0).
Modifications to the VAX-31 infant Phase 2 study—adding an optimized dose arm and removing the low-dose arm—have pushed expected topline safety and immunogenicity data to the first half of 2027, delaying progression to a pediatric Phase 3 program and potential market entry (Nasdaq via turn8search0).
Operating expenses accelerated sharply in Q2 2025, with total GAAP operating costs rising to $226.2 million from $153.0 million a year earlier, driven by a 47.7% increase in R&D and 48.8% in G&A expenses, heightening cash burn and potentially eroding the company’s runway absent further capital raises (Nasdaq via turn8search0).
Data summarised monthly by Lightyear AI. Last updated on 1 Sept 2025.

Vaxcyte Financial Performance

Revenues and expenses
QuarterlyAnnual
Q3 24
QoQ growth
Revenue
$37B
-39.75%
Net income
$45B
107.52%
Profit margin
37.65%
6.78%

Vaxcyte Earnings Performance

Company profitability
QuarterlyAnnual
Q4 23
Q1 24
Q2 24
Q3 24
Q4 24
Actual
$3.69
$2.85
$2.45
$2.42
-
Expected
$3.55
$2.61
$2.05
$2.31
$3.94
Surprise
3.94%
9.20%
19.51%
4.63%
-
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
Real-time US market data is sourced from the IEX order book provided by Polygon. After-hours US market data is 15 minutes delayed and may differ significantly from the actual tradable price at market open.

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