Ventyx Biosciences/$VTYX

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About Ventyx Biosciences

Ventyx Biosciences Inc is a clinical-stage biopharmaceutical company focused on advancing new therapies for millions of patients living with inflammatory diseases and autoimmune, and neurodegenerative disorders. The company is developing a pipeline of novel small-molecule product candidates to address a range of inflammatory diseases. Its product candidate VTX958 is an oral, selective clinical-stage tyrosine kinase type 2 (TYK2) inhibitor designed to inhibit TYK2 without detectable inhibition of other Janus kinase (JAK) isoforms, which avoids toxicities associated with broader JAK inhibition and, thus, other JAK inhibitors.

Ticker

$VTYX
Sector
Primary listing

Employees

81

VTYX Metrics

BasicAdvanced
$587M
-
-$1.68
0.97
-

What the Analysts think about VTYX

Analyst ratings (Buy, Hold, Sell) for Ventyx Biosciences stock.

Bulls say / Bears say

A $27 million strategic investment by Sanofi in September 2024 validated VTX3232’s potential, extended Ventyx’s cash runway at least into H2 2026, and gave Sanofi exclusive first-negotiation rights on the CNS-penetrant NLRP3 program (Nasdaq)
Data presented at ECCO 2025 showed VTX958 achieved statistically significant reductions in endoscopic SES-CD scores compared to placebo (–3.5 and –2.7 points for 225 mg and 300 mg BID, respectively; p < 0.0005), clearly demonstrating mucosal healing in Crohn’s disease (Journal of Crohn’s and Colitis via Ventyx IR release)
Ventyx ended Q2 2025 with $209.0 million in cash, cash equivalents, and marketable securities—providing funding through H2 2026 to support several upcoming Phase 2 readouts in its NLRP3, TYK2, and S1P1R programs (Ventyx IR release)
VTX958 failed to meet the primary endpoint in its Phase 2 Crohn’s disease trial, with CDAI reductions of –134.1 (225 mg) and –113.6 (300 mg) compared to –104.3 for placebo (p > 0.05), casting doubt on its efficacy in IBD indications (Journal of Crohn’s and Colitis via Ventyx IR release)
Ventyx reported a net loss of $27.0 million in Q2 2025, highlighting ongoing high operating costs and continued pressure on liquidity, despite improving from a $32.0 million loss the prior year (Ventyx IR release)
VTYX shares have traded in a wide 52-week range—from $0.78 to $3.39—showing significant price volatility and continued market skepticism about the company’s clinical and commercial outlook (CNBC)
Data summarised monthly by Lightyear AI. Last updated on 25 Oct 2025.

VTYX Financial Performance

Revenues and expenses
QuarterlyAnnual
Q3 24
QoQ growth
Revenue
$37B
-39.75%
Net income
$45B
107.52%
Profit margin
37.65%
6.78%

VTYX Earnings Performance

Company profitability
QuarterlyAnnual
Q4 23
Q1 24
Q2 24
Q3 24
Q4 24
Actual
$3.69
$2.85
$2.45
$2.42
-
Expected
$3.55
$2.61
$2.05
$2.31
$3.94
Surprise
3.94%
9.20%
19.51%
4.63%
-
Data displayed above is indicative only and its accuracy or completeness is not guaranteed. Actual execution price may vary. Past performance is not indicative of future results. Your return may be affected by currency fluctuations and applicable fees and charges. Capital at risk.
Real-time US market data is sourced from the IEX order book provided by Polygon. After-hours US market data is 15 minutes delayed and may differ significantly from the actual tradable price at market open.

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