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Novartis AG is a Swiss multinational pharmaceutical company headquartered in Basel, Switzerland. It operates primarily in the healthcare industry, focusing on the research, development, and manufacturing of a wide range of prescription medications targeting oncology, immunology, neuroscience, and cardiovascular diseases. Key products include Cosentyx (for psoriasis and arthritis) and Entresto (for heart failure). Founded in 1996 through the merger of Ciba-Geigy and Sandoz, Novartis has a significant geographic presence, with operations in over 100 countries. A key competitive strength of the company is its strong investment in research and development, which underpins its substantial portfolio of innovative therapies.

AbbVie is a pharmaceutical firm with a strong exposure to immunology (with Humira, Skyrizi, and Rinvoq) and oncology (with Imbruvica and Venclexta). The company was spun off from Abbott in early 2013. The 2020 acquisition of Allergan added several new products and drugs in aesthetics, including Botox. The 2024 acquisitions of Cerevel (neuroscience) and ImmunoGen (oncology) help supplement AbbVie's portfolio.