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Cogent Biosciences Inc a biotechnology company focused on developing precision therapies for genetically defined diseases. It designs rational precision therapies that treat the underlying cause of disease and improve the lives of patients. Its program CGT9486, is a selective tyrosine kinase inhibitor designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. In the vast majority of cases, KIT D816V is responsible for driving Systemic Mastocytosis (SM), a serious disease caused by the unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with dependence on oncogenic KIT signaling.

Johnson & Johnson je največje in najbolj raznoliko zdravstveno podjetje na svetu. Ima dva oddelka: inovativna zdravila in medicinska tehnologija. Po odprodaji dejavnosti potrošniških izdelkov Kenvue v letu 2023 ta oddelka zdaj predstavljata celotno prodajo podjetja. Po prestrukturiranjih v letih 2023–24 se oddelek za zdravila osredotoča na tri glavna terapevtska področja: imunologijo, onkologijo in nevrologijo. Geografsko gledano se nekaj več kot polovica skupnih prihodkov ustvari v Združenih državah Amerike.